Advantages of using the Harmony AFS Device for photodynamic therapy with a wavelength of 660 nm and 400 nm

  • Photodynamic therapy (PDT) is a new effective organ-preserving method for the treatment of various diseases, both malignant tumors and a number of non-tumor diseases. It is successfully used in the treatment of joint diseases, providing anti-inflammatory, analgesic, decongestant, regenerative, immunomodulatory effects without adverse effects on healthy tissues and other organs and systems.

  • Unlike traditional methods of treatment, photodynamic therapy is characterized by high selectivity, low toxicity of the administered drugs, high efficiency, and the ability to conduct several sessions without side effects on the cardiovascular, urinary, nervous system, and gastrointestinal tract.

The essence of the method is that the photosensitizer, which has a unique property of selectively accumulating in tissues with increased metabolism, is activated by local irradiation of pathologically altered tissues with light with a wavelength corresponding to the long-wave absorption peak of the photosensitizer. The photochemical reaction that occurs in the presence of oxygen in the tissues themselves causes the generation of singlet oxygen and other reactive oxygen species that have a detrimental effect on pathological tissues with increased metabolism, for example, on rheumatoid. The action of reactive oxygen species is manifested by direct cytotoxic damage to cells or by destruction (destruction) of inflamed tissues. In addition, a whole cascade of immunological reactions develops during PDT. Photodynamic therapy opens up wide opportunities for various therapeutic effects of a radical and palliative nature, when other methods of treatment have already exhausted themselves or are not applicable at all.